Pediatric Cancer Research

Pedals for Pediatrics has directed over $1 million for pediatric cancer research.  

Below are some examples of recently funded research grants:

 

PMC Year

Program

Designee

Amount

Description

2008

Tissue Bank initiative

Mark Kieran, MD

100,000

AV/telemedicine equipment to support development of research tissue bank

2009

Robot liquid handler

Brian Crompton, MD

65,000

Research lab equipment

 

Patient Fatigue study

Margaret McCabe, PhD, RN

23,500

Fatigue in hospitalized children with cancer

         

2010

Community Outreach Program Evaluation

Patricia Branowicki, PhD RN

50,000

Impact of community services on patient outcomes (allocated over 3 years)

 

Quality of Life after Cure

Christopher Recklitis, PhD, MPH

10,000

Quality of life in brain tumor survivors

2011

       
 

Progostic effect of tumor histology following induction therapy for high risk neuroblastoma

Rani George, MD

5,000

Determine whether tumor histology can predict outcome in high risk NB

 

Establishing autonomous healthcare in adolescent/young adult survivors

Lisa Kenney, MD

3,000

Survey cancer survivors about their attitudes/preferences around transition to adult health care

 

Economic Resource Needs in Families of Children Newly Diagnosed with Cancer

Kira Bona, MD

15,000

Determine the impact of the first 6 months of cancer tx on familial income, savings, financial stability

 

Outpatient Central-Line Associated Blood Stream Infections (CLABSI)

Laura McCullough, MD and Amy Billett, MD

12,500

Track patients with central lines, investigate ambulatory line infections, implement education to reduce line infections

 

Pre-Clinical Testing of Targeted Therapy in Ewing Sarcoma

Brian Crompton, MD

20,000

Test the effect of GSK 2256098 treatment on mice with Ewing sarcoma

 

Assessing pain in pediatric brain tumor survivors

Peter Manley, MD

7,000

Assess prevalance of pain in childhood brain tumor survivors, risk factors associated with pain

 

Pediatric Rhabdomyosarcoma (RMS): Can we learn more about tumor biology and outcomes through international collaborations?

Paola Friedrich-Medina, MD; Carlos Rogriguez-Galindo, MD

7,000

Describe characteristics of RMS in Central America; correlate with geographic, socioeconomic and ethic factors

2012

Pediatric craniopharyngioma

Peter Manley, MD

40,000

 
 

Osteosarcoma genetic vulnerabilities

Jennifer Perry, MD

40,000

 
 

Y Apoptosis targeted therapy in ALL

Yana Pikman, MD

40,000

 

2013

Investigation of Druggable Epigenetic Targets in High-Grade Glioma

Adam Green, MD

50,000

 
 

Development of a pediatric cancer unit performance index

Paola Friedrich-Medina, MD

50,000

 
 

Insomnia after childhood cancer: A cognitive-behavioral pilot intervention

M. Zhou, MD

50,000

 
 

Identification of Molecular Therapeutic Targets in Pediatric Adrenocarcinoma

Carlos Rodriguez-Galindo, MD

25,000

 
         

2014

Therapeutic Targeting of Oncogenic Hedgehog Signaling in T-Cell Acute Lymphoblastic Leukemia

Melissa Burns, MD

50,000

 
 

A Phase I Trial of Low-Dose Interleukin-2 (IL-2) for Steroid-Refractory Chronic Graft-versus-Host-Disease in Children

Jennifer Whangbo, MD

50,000

 
 

1 year funding

     
 

Assessing drivers of tumor progression in peripheral nerve sheath tumors

Andrew Hong, MD

25,000

 
 

Sexual Health in Young Adult Survivors of Childhood Cancer

Natasha Frederick, MD

25,000

 
         

2015

A novel target for telomerase inhibition in cancer

Suneet Agarwal, MD

50,000

 
 

Identifying Mechanisms of Resistance to JAK2 Inhibition in CRLF2-Rearranged B-ALL

Loretta Li, MD

     40,000

 
 

Patient and Parent Perspectives on Genomic Tumor Profiling (GTP) of Pediatric Solid Tumors

Jonathan M. Marron, MD

50,000

 
 

Treatment preferences of parents of children with cancer: What risks of late effects are parents willing to accept in exchange for improved survival?

Katie Greenzang, MD

50,000

 
         

2016

Basic/Translational

     
 

Modeling Pediatric myelodysplastic syndromes in zebrafish

      Serine Avagyan, MD

40,000

20K x 2 years

 

Atlas of Pediatric Tumor Immunity

Natalie Collins, MD

50,000

25K x 2 years

 

Epidemiology/Clinical

     
 

Socioeconomic status and adherence to oral chemotherapy in childhood ALL

Kira Bona, MD

22,500

 
 

Improving Adolescent and Young Adult Oncology Patient Quality of Life through Enhanced Patient-Provider Communication

Natasha N. Frederick, MD

22,500

 
 

Formative Research for a Symptom Management Intervention in Pediatric Stem Cell Transplant

Christina Ullrich, MD

25,000

 

2017

The Role of the Hematopoietic Microenvironment in Infant Leukemia

Grant Rowe, MD

 

50,000

25K x 2 yrs

 

The Day 100 Talk: A pilot feasibility study of a communication intervention targeting the early treatment period in pediatric oncology

Angela Feraco, MD

50,000

25k x 2 yrs

 

Genomic Screening to Inform Synergistic Combinations in Ewing Sarcoma

Lilly  Guenther, MD

25,000

 

 

Nursing Research Fellowships: Validation of a Tool to Measure Nausea

Gwendolyn Corr, NP

10,000

 

         
   

Total

$1,383,000