Pediatric Cancer Research

Pedals for Pediatrics has directed over $1 million for pediatric cancer research.  

Below are some examples of recently funded research grants:



PMC Year

Program

Designee

Amount

Description

2008

Tissue Bank initiative

Mark Kieran, MD

100,000

AV/telemedicine equipment to support development of research tissue bank

2009

Robot liquid handler

Brian Crompton, MD

65,000

Research lab equipment

Patient Fatigue study

Margaret McCabe, PhD, RN

23,500

Fatigue in hospitalized children with cancer

2010

Community Outreach Program Evaluation

Patricia Branowicki, PhD RN

50,000

Impact of community services on patient outcomes (allocated over 3 years)

Quality of Life after Cure

Christopher Recklitis, PhD, MPH

10,000

Quality of life in brain tumor survivors

2011

Progostic effect of tumor histology following induction therapy for high risk neuroblastoma

Rani George, MD

5,000

Determine whether tumor histology can predict outcome in high risk NB

Establishing autonomous healthcare in adolescent/young adult survivors

Lisa Kenney, MD

3,000

Survey cancer survivors about their attitudes/preferences around transition to adult health care

Economic Resource Needs in Families of Children Newly Diagnosed with Cancer

Kira Bona, MD

15,000

Determine the impact of the first 6 months of cancer tx on familial income, savings, financial stability

Outpatient Central-Line Associated Blood Stream Infections (CLABSI)

Laura McCullough, MD and Amy Billett, MD

12,500

Track patients with central lines, investigate ambulatory line infections, implement education to reduce line infections

Pre-Clinical Testing of Targeted Therapy in Ewing Sarcoma

Brian Crompton, MD

20,000

Test the effect of GSK 2256098 treatment on mice with Ewing sarcoma

Assessing pain in pediatric brain tumor survivors

Peter Manley, MD

7,000

Assess prevalance of pain in childhood brain tumor survivors, risk factors associated with pain

Pediatric Rhabdomyosarcoma (RMS): Can we learn more about tumor biology and outcomes through international collaborations?

Paola Friedrich-Medina, MD; Carlos Rogriguez-Galindo, MD

7,000

Describe characteristics of RMS in Central America; correlate with geographic, socioeconomic and ethic factors

2012

Pediatric craniopharyngioma

Peter Manley, MD

40,000

Osteosarcoma genetic vulnerabilities

Jennifer Perry, MD

40,000

Y Apoptosis targeted therapy in ALL

Yana Pikman, MD

40,000

2013

Investigation of Druggable Epigenetic Targets in High-Grade Glioma

Adam Green, MD

50,000

Development of a pediatric cancer unit performance index

Paola Friedrich-Medina, MD

50,000

Insomnia after childhood cancer: A cognitive-behavioral pilot intervention

M. Zhou, MD

50,000

Identification of Molecular Therapeutic Targets in Pediatric Adrenocarcinoma

Carlos Rodriguez-Galindo, MD

25,000

2014

Therapeutic Targeting of Oncogenic Hedgehog Signaling in T-Cell Acute Lymphoblastic Leukemia

Melissa Burns

50,000

A Phase I Trial of Low-Dose Interleukin-2 (IL-2) for Steroid-Refractory Chronic Graft-versus-Host-Disease in Children

Jennifer Whangbo

50,000

1 year funding

Assessing drivers of tumor progression in peripheral nerve sheath tumors

Andrew Hong

25,000

Sexual Health in Young Adult Survivors of Childhood Cancer

Natasha Frederick

25,000

2015

A novel target for telomerase inhibition in cancer

Suneet Agarwal

50,000

Identifying Mechanisms of Resistance to JAK2 Inhibition in CRLF2-Rearranged B-ALL

Loretta Li

40,000

Patient and Parent Perspectives on Genomic Tumor Profiling (GTP) of Pediatric Solid Tumors

Jonathan M. Marron

50,000

Treatment preferences of parents of children with cancer: What risks of late effects are parents willing to accept in exchange for improved survival?

Katie Greenzang

50,000

2016

Basic/Translational

MODELING PEDIATRIC MYELODYSPLASTIC SYNDROMES IN ZEBRAFISH

SERINE AVAGYAN

40,000

20K x 2 years

Atlas of Pediatric Tumor Immunity

Natalie Collins

50,000

25K x 2 years

Epidemiology/Clinical

Socioeconomic status and adherence to oral chemotherapy in childhood ALL

Kira Bona

22,500

Improving Adolescent and Young Adult Oncology Patient Quality of Life through Enhanced Patient-Provider Communication

Natasha N. Frederick

22,500

Formative Research for a Symptom Management Intervention in Pediatric Stem Cell Transplant

Christina Ullrich

25,000

2017

TBD

135,000

Total

$1,248,000